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Public Health

Elsevier BV

Preprints posted in the last 30 days, ranked by how well they match Public Health's content profile, based on 34 papers previously published here. The average preprint has a 0.04% match score for this journal, so anything above that is already an above-average fit.

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Intention of UK residents to wear facemasks and practise social distancing during the next respiratory virus pandemic

Smith, D. R.; Buckell, J.; Hancock, T. O.; Morrell, L.; Pouwels, K.

2026-05-30 public and global health 10.64898/2026.05.21.26353824 medRxiv
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Background: Wearing facemasks and practising social distancing slow the spread of respiratory pathogens. However, in the event of a new pandemic emerging, the willingness of populations to voluntarily adopt these behaviours is unclear. Methods: A discrete choice experiment was conducted among 2,006 UK-based adults. Participants were presented with hypothetical scenarios describing the emergence of a respiratory virus pandemic and were asked to choose when they would wear facemasks and practise social distancing. A mixed multinomial logit model was used to jointly estimate how disease severity and prevalence, uncertainty in these quantities, and individual-level characteristics influence behavioural choices. Findings: Participants were averse to facemasks and social distancing in the absence of pandemic risk. For each ten-unit increase in severity (10 additional hospitalisations/1,000 infections), the odds of always wearing a facemask outside the home increased by 15.9% (95%CI: 14.3%, 17.5%), relative to rarely/never, and the odds of avoiding all people as much as possible increased by 16.4% (14.6%, 18.2%), relative to not avoiding anyone. Greater disease prevalence, uncertainty in disease severity or disease prevalence, a university education, prior COVID-19 vaccination and non-white ethnicity were also associated with choosing to always wear facemasks and avoid all people as much as possible. The probability of participants choosing to rarely/never wear facemasks varied from 13.4% (11.9%, 14.9%) in the lowest-risk scenario to 1.4% (1.2%, 1.7%) in the highest-risk scenario. Interpretation: Perceived risks of disease and associated uncertainty drive intention of UK adults to adapt their behaviour in a future pandemic.

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When advantage turns into risk: disentangling landscape and behavioural drivers of socioeconomic inequality in Lyme disease risk, Glasgow as a case study

Gandy, S. L.; Plahe, G.; Hall, J.; Watkinson, K.; Guntupalli, S.; Johnson, D.; Birtles, R.; Mavin, S.; Gilbert, L.

2026-05-21 public and global health 10.64898/2026.05.18.26353476 medRxiv
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Introduction: Socioeconomic deprivation is often associated with poorer health outcomes, but some studies suggest the opposite for Lyme disease. Here we test two hypotheses to explain this: differences in (i) local landcover of high risk habitats such as woodlands (landscape hypothesis) and (ii) outdoor recreation in such habitats (behaviour hypothesis). Methods: We analysed reported Lyme disease incidence data for 824 data zones in the city of Glasgow, UK, against deprivation rank (based on indicators relating to income, employment, health, education, crime and housing). We then tested how these relate to woodland cover and indices of urban greenspace usage (per capita and per ha of greenspace). Additionally, we measured Lyme disease hazard (density of infected ticks) in 32 greenspaces and tested relationships with deprivation, woodland and greenspace usage. Results: More advantaged data zones (data zones with low deprivation rank) had higher Lyme disease incidence. These areas had more woodland and woodland cover was positively correlated with both Lyme disease incidence and hazard. Deprivation did not correlate with greenspace usage, nor did greenspace usage correlate with Lyme disease incidence. Intensely used greenspaces had lower infected tick densities, consistent with a human disturbance effect on wildlife that carry ticks. Conclusions: Differences in woodland cover, but not outdoor recreation behaviour, can help explain our finding of higher Lyme disease incidence in more advantaged areas. However, to further test the behaviour hypothesis, we need more detailed data on outdoor recreation activity per capita both locally and in rural areas, as well data on mitigation behaviours.

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Exploring emergency department attendance patterns during the UEFA European Football Championship 2024 in Germany

Charfeddine, N.; Schranz, M.; Schlump, C.; Rupprecht, M.; Ullrich, A.; Diercke, M.; AKTIN Research Group, ; Estupinan Mendez, J.

2026-06-09 epidemiology 10.64898/2026.06.08.26355151 medRxiv
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Background: Mass gathering events (MGEs) are associated with several public health challenges and may cause a strain on healthcare services. Literature findings on the impact of MGEs on emergency departments (EDs) are heterogeneous. Objectives: To examine shifts in ED attendance characteristics during a major sporting tournament, namely the UEFA European Football Championship 2024 held in Germany. Methods: We conducted a retrospective observational study using ED data from the Emergency Department Data Registry. We compared baseline ED attendance characteristics between the tournament and the reference period, defined as two weeks before and two weeks after the tournament, and between Germany game days and non-Germany game days. Hourly attendance patterns were analysed for all Germany games using a reference range. Results: We included data from 41 EDs, totalling 253,493 attendances during the study period. A 1.57% increase in attendance was observed during the tournament compared to the reference period, with baseline characteristics remaining similar. The median daily attendance within all EDs was slightly lower on Germany game days (4066) compared to non-Germany game days (4128). Modest changes were observed in the hourly attendance on Germany game days, most notable during the last Germany game where a decrease in attendance below the reference range extended over three hours. Conclusions: The observed shifts in ED attendance were minimal, suggesting that no major changes of public health relevance occurred in ED attendance during the tournament. We highlight the utility of using ED data for monitoring and for enhancing the understanding of the public health risks and challenges associated with MGEs.

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Determinants of in-hospital mortality within 48 hours of admission to the Emergency and Urgent Care Department at University Teaching Hospital, Lusaka, Zambia: a retrospective cross-sectional study

Tambo, J. M.

2026-05-12 public and global health 10.64898/2026.05.07.26352696 medRxiv
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BackgroundThe emergency department (ED) serves as a critical entry point into hospital care and a sentinel indicator of health system performance. In-hospital mortality within 48 hours of ED admission represents acute care failures that are often preventable yet remain poorly characterized in sub-Saharan African (SSA) settings. This study aimed to identify the demographic, clinical, and hospital-related determinants of in-hospital mortality within 48 hours of admission to the Emergency and Urgent Care Department at the University Teaching Hospital (UTH), Lusaka, Zambia. MethodsA retrospective cross-sectional study was conducted using 385 patient records from UTHs Emergency and Urgent Care Department for the year 2021. Data were extracted from the District Health Information System 2 (DHIS2) using simple random sampling. Descriptive statistics, univariate, and multivariable logistic regression analyses were performed using STATA 16.1 MP. Variables with p<0.20 in univariate analysis were retained for adjusted modelling. Multicollinearity was assessed via variance inflation factors (VIF <5). Model fit was evaluated using the Hosmer-Lemeshow goodness-of-fit test and receiver operating characteristic (ROC) analysis. ResultsOf 385 patients, 175 (45.5%) died within 48 hours of admission. Patients who died were older (median age 45 vs. 37.5 years, p<0.001). In multivariable analysis, three variables were independently associated with 48-hour mortality: pulse rate (aOR = 0.98, 95% CI: 0.95-1.00, p = 0.036), Glasgow Coma Scale (GCS) score (aOR = 0.75, 95% CI: 0.63-0.90, p = 0.002), and out-of-hours admission between 00:00-07:59 (aOR = 11.44, 95% CI: 1.19-109.96, p = 0.035). Age was a significant predictor in univariate analysis but not in the adjusted model, indicating confounding. The model demonstrated good discriminatory ability (AUC = 0.81). ConclusionsReduced pulse rate, lower GCS score at admission, and out-of-hours presentation are independent determinants of 48-hour in-hospital mortality at UTH. These findings underscore the need for enhanced vital sign monitoring protocols, targeted staffing during overnight hours, and improved risk stratification tools in resource-constrained emergency care settings. The wide confidence interval for the time-of-admission finding warrants cautious interpretation and validation in future prospective studies.

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Meningitis vaccination campaign in the context of COVID-19 in Cameroon

Mbang, M. A.; Cheuyem, F. Z. L.; Tchamani, R.; Debnet, J.; Ebongo, Z. N.; Fouda, A. A. B.

2026-06-04 public and global health 10.64898/2026.06.02.26354702 medRxiv
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Objective: The study aimed to describe the challenges, best practices, and lessons learned during meningitis vaccination campaigns conducted in the context of COVID-19 in Cameroon in 2020. Results: During the prevention campaigns, 3,460 individuals were selected. All were tested before the campaign (100%). Eight cases were positive, representing a positivity rate of 0.23% (8/3,460). The campaign was carried out using a fixed strategy in health facilities and prisons and a fixed-temporary strategy in communities. Most health areas received sufficient quantities of COVID-19 equipment for some items and insufficient quantities for others. No screening was done during or after the campaign. The main difficulties encountered were compliance with social distancing and the continuous wearing of gowns. The challenges faced were the screening of actors and the use of personal protective equipment. Lessons learned: aspects related to COVID-19 impacted the speed of the campaign. Vaccination coverage ranged from 91% to 140% in prisons on the one hand, and from 35% to 112% in the health areas surrounding prisons on the other. The campaign in the context of COVID-19 was effective. Compliance with barrier measures was not optimal due to difficulties encountered with aspects such as social distancing, continuous wearing of gowns, screening of participants during and after the campaign, and insufficient personal protective equipment.

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Associations between lack of social support and food insecurity: A cross-sectional analysis of the 2024 BRFSS

Krishna, E. S. C.; Shanavas, N.; Mir, F.; Kothapeta, A.; Duluc, C.; Kale, R.; Bheemanakunta, P.; Mathur, E.

2026-05-27 public and global health 10.64898/2026.05.24.26353990 medRxiv
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Objective: To verify the association between perceived social & emotional support and self-reported food insecurity in the United States Design: Cross-sectional secondary data analysis Setting: Behavioral Risk Factor Surveillance System (BRFSS) data from 2024, collected via a nationwide telephone survey. Food insecurity was defined as responding always, usually, or sometimes to "During the past 12 months how often did the food that you bought not last, and you didn't have money to buy more?" Social support was measured using a BRFSS item assessing the frequency with which respondents received the social and emotional support they needed. Adjusted logistic regression models were used to assess the relationship between these variables while controlling for a wide variety of demographic, socioeconomic, and health status factors. Participants: Adults (n = 190,577) aged 18-80 years old (72.3% non-Hispanic White) Results: Individuals who reported only "sometimes" receiving the social and emotional support they need were more likely to report food insecurity as compared to those who "always" receive such support (aOR = 1.75; 95% CI 1.56, 1.96). Conclusions: These findings indicate that decreased social support may put individuals at higher risk of food insecurity. Future work should seek to understand the mechanisms of this association to inform targeted policy and other interventional programs.

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Impact of minimum wage increases on homicide mortality in the US

Fitch, K. V.; Santaularia Gomez, N. J.; Tanveer, M.; Holmes, G. M.; Moracco, K. E.; Fliss, M. D.; Fulcher, N.; Ranapurwala, S. I.

2026-05-24 health policy 10.64898/2026.05.21.26353800 medRxiv
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Introduction: Even though state minimum wage (MW) is a policy lever that affects income and poverty and can prevent of violence, no prior study has comprehensively evaluated its impact in the United States (US). In this study, we estimated the impact of at least a $1 USD increase in state MW above the federal MW on overall, firearm, and non-firearm homicide mortality and examined its impact on racialized inequities. Methods: We conducted a quasi-experimental study using controlled interrupted time series (CITS) and synthetic controlled interrupted time series (SCITS) approaches to examine immediate and sustained impact of state MW increases. We used state-month level homicide victimization mortality data from 2010-2019. Homicide victimization death was identified using International Classification of Disease codes, 10th revision. State MW data was obtained from the Bureau of Labor Statistics. Results: Demographic and social variables from intervention, never-exposed, and always-exposed states were similar to each other and representative of the total US population from all 50 states. The CITS results show that after MW increases in the intervention states, these states experienced a sustained decline of -0.22 (-0.37, -0.07) homicide victimizations/ 100,000 person-years/ year relative to the never-exposed states and -0.39 (-0.59, -0.18) relative to always-exposed states. This resulted in 5,657 fewer homicide victimization deaths in the intervention states over four years of post-MW increase period compared to the never-exposed states. SCITS results were similar to the CITS results, and the majority of sustained declines were observed in firearm-related deaths and among Black population. Conclusion: MW increase was associated with a reduction in homicide victimization rates, which were robust in multiple sensitivity analyses, more pronounced for firearm-related homicide deaths, and reduced homicide victimization inequities for Black Americans.

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Knowledge, Attitudes, and Practices regarding Antibiotic Use and Antimicrobial Resistance (AMR) in Nepal

Thapa, D.; Magar, M. B.

2026-05-29 public and global health 10.64898/2026.05.27.26354255 medRxiv
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Background: Antimicrobial resistance is the world's silent pandemic. The public knowledge, attitudes, and practices (KAP) about antibiotic usage are strongly related to the growing problem in Nepal. Methods: A cross-sectional descriptive survey was done to 263 respondents. Information on KAP regarding antibiotics, primary healthcare sources, and demography was collected through a questionnaire. To identify health literacy gaps and characteristics that contribute to improper antibiotic use, this study assessed these variables across an age group from 18 to 60 years. Descriptive statistics analysis was performed to analyze the data. Results: The majority of respondents were between the ages of 18 and 39 (85.1%), female (63.1%), and had at least a bachelor's degree (67.8%). Significant misunderstandings about antibiotics remained, even though 77.6% of respondents correctly recognized antibiotics as effective against bacteria; 44.1% incorrectly believed that antibiotics cure viral diseases, and 87.8% felt that antibiotics should be stopped right away if adverse effects develop. In practice, 52.9% acknowledged quitting antibiotics as soon as symptoms improved, despite 89.4% consulting doctors. Additionally, 43% of respondents said they have taken antibiotics without a prescription, frequently due to pharmacist recommendations (21.67%) and financial or geographical constraints. The main sources of information were doctors (11.07%) and pharmacist-doctor combinations (14.88%), yet 81.8% of respondents said they had never heard of the phrase antimicrobial resistance. Conclusion: There is a significant lack between theoretical understanding and practical application, despite the high levels of fundamental knowledge toward the prohibition of non-prescription sales. Self-medication and early withdrawal are still common inappropriate practices. It is crucial to implement focused teaching initiatives that highlight the differences between bacterial and viral diseases as well as the risks associated with leftover medicine. It is advised to use digital platforms for younger demographics and to strengthen the role of pharmacists in order to reduce AMR.

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Occupational hierarchy, racialization, and COVID-19 health outcomes among meat processing plant workers in Alberta: a community-engaged mixed-methods study

Essar, M. Y.; Norrie, E.; Cerino, E. R.; Antonio, M.; Saad, A.; Yemane, M.; Holdbrook, L.; Sahilie, A.; Youssef, M.; Hassan, N.; Magwood, O.; Edwards, S. T.; Spitzer, D.; Coakley, A.; Pottie, K.; Fabreau, G. E.

2026-05-20 public and global health 10.64898/2026.05.14.26353257 medRxiv
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Background Meat processing plants in Alberta, Canada experienced among North America's largest COVID-19 outbreaks. We examined health impacts among workers by occupational hierarchy and equity-relevant characteristics. Methods This exploratory sequential mixed-methods study was guided by community-based participatory research and the PROGRESS-Plus framework. Multilingual qualitative interviews and surveys using validated instruments were conducted among meat plant workers who experienced outbreaks. Interviews were analysed using inductive-deductive thematic analysis. Multivariable logistic regression and linear regression estimated associations between occupational group, racialization, facility, and self-reported COVID-19 diagnosis, physical and mental health, and mean Everyday Discrimination Scale score. We integrated findings using joint displays. Findings Qualitative and integrated analysis of thirty-six interviews described occupational hierarchy shaping unequal protection, limited communication, constrained agency, and psychosocial harms, amplified by income insecurity and family separation. Among 187 survey respondents, compared with general labour, skilled labour (aOR 0.38; 95% CI 0.15-0.89) and management (aOR 0.13; 95% CI 0.01-0.75) had lower odds of reported COVID-19 diagnosis. Compared with Black workers, other racialized workers had lower odds of reporting fair or poor mental (aOR 0.24; 95% CI 0.09-0.58) and physical health (aOR 0.20; 95% CI 0.06-0.54). Compared with workers from the primary facility, others reported lower mean everyday discrimination scores ({beta} = -0.54; 95% CI -0.96 to -0.12). Interpretation COVID-19 harms followed workplace social hierarchies. Pandemic preparedness should combine infection-control measures with paid sick leave and income protection, multilingual communication, enforceable anti-discrimination standards, and independent reporting mechanisms. Funding Canadian Institutes for Health Research (CIHR Application no. 469206). Keywords COVID-19, immigrant workers, migrants, essential workers, health equity, occupational health, PROGRESS Plus

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Physical activity, sedentary behaviour, and health inequalities among Somali residents in Sheffield, United Kingdom: a mixed-methods study

Falobi, A. A.; Hersi, O. O.; Ojo, O.

2026-05-21 public and global health 10.64898/2026.05.18.26353489 medRxiv
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Background Physical inactivity and sedentary behaviour are major contributors to non-communicable diseases (NCDs) and are unevenly distributed across populations, disproportionately affecting migrants and ethnic minority groups. Somali communities in the UK experience multiple structural and socio-economic disadvantages; however, evidence on physical activity and associated inequities remains limited. This study examined physical activity, sedentary behaviour, and related barriers and facilitators among Somali residents in Sheffield, United Kingdom. Methods A cross-sectional mixed-methods study was conducted among Somali adults (n = 238). Quantitative data were collected using the International Physical Activity Questionnaire Short Form (IPAQ-SF) and analysed using descriptive statistics and ordinal logistic regression. Qualitative data were obtained from two focus group discussions (n = 14) and analysed using inductive thematic analysis to explore socio-cultural, environmental, and structural determinants of physical activity. Results No statistically significant predictors of physical activity were identified in the adjusted analysis; however, consistent trends indicated lower activity levels among older adults and those in employment. Qualitative findings revealed multiple, intersecting barriers rooted in structural inequities, including migration-related lifestyle changes, reduced incidental activity, sedentary occupations, limited health literacy, language barriers, financial constraints, and gendered responsibilities. Cultural norms and environmental conditions further shaped behaviour. Facilitators included community-based, culturally tailored interventions, peer support, gender-sensitive programmes, and adaptation of traditional practices. Conclusion Somali residents in Sheffield face overlapping structural and socio-cultural barriers to physical activity that are not fully captured by quantitative measures alone. Equity-oriented, culturally competent, and community-led interventions addressing both systemic and behavioural determinants are essential to improve access to physical activity and reduce health inequalities and NCD risk.

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Optimizing Ambulatory Groin Hernia Repair in Public Healthcare Frameworks: A Prospective Analysis of Predictive Factors for Discharge Failure

Krichen, J.; SGHAIER, A.; Dhouib, R.; Souii, S.; Tioumi, M.; Sindi, S.; Faidi, B.; Ben Salah, K.

2026-05-29 public and global health 10.64898/2026.05.27.26354207 medRxiv
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Background Outpatient groin hernia repair is widely recommended globally due to clinical and socioeconomic efficiency, yet it remains underutilized in developing healthcare systems like Tunisia. This study aimed to evaluate the feasibility of a newly implemented day-surgery clinical pathway for groin hernias and identify specific predictors associated with outpatient discharge failure. Methods A prospective, observational cohort study was conducted at a Tunisian tertiary hospital between September 2023 and April 2024. A total of 85 consecutive patients scheduled for elective groin hernia repair under an optimized clinical pathway were enrolled. Inclusion criteria spanned ASA classes I-III, age [&ge;]16 years, proximity to the hospital [&le;]50 km), and presence of a literate adult caregiver. Outpatient failure (unanticipated admission) was defined as the inability to achieve discharge within 24 hours post-surgery. Statistical associations were determined using Chi-squared, Fisher's exact, and independent t-tests. Results The cohort primarily comprised males (n = 82, 96.5%) with a mean age of 56 years (range: 19-86). Successful ambulatory discharge was achieved in 80 patients (94.1%), yielding a failure rate of 5.9% (n = 5). Unanticipated admissions were triggered by uncontrolled pain (n = 1), acute anxiety (n = 2), decompensation of comorbidities (n = 1), and a Post-Anesthetic Discharge Scoring System (PADSS) score < 10 (n = 1). Overall 30-day morbidity was low (2.4%), presenting as minor wound or scrotal hematomas managed conservatively; no surgical site infections, acute urinary retention, or mortality occurred. Univariate analysis revealed that a hernial sac size measured at its maximum diameter between 1.5 and 3 cm was significantly associated with ambulatory failure (p = 0.047). General anesthesia showed a trend toward increased failure compared to regional anesthesia (p = 0.08). Conclusion Day-surgery groin hernia repair is highly safe and feasible in resource-constrained environments, even for elderly or stable ASA III patients, provided rigorous social criteria are satisfied. A small hernial sac size (1.5-3 cm) constitutes a major anatomical predictor of failure, likely due to distinct dissection dynamics and localized post-operative pain profiles.

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Does Parental Migration Affect a Child's Immunization Coverage? A Cross-sectional Analytical Study of India

Dhalaria, P.; Kumar, P.; Kapur, S.; Verma, A. K.; Singh, A. K.; Priyadarshini, P.; Singh, K.; Tripathi, B.; Ray, A.

2026-05-20 public and global health 10.64898/2026.05.14.26353222 medRxiv
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Introduction-India's immunization initiatives are among the largest globally, characterized by a substantial birth cohort of 27 million children annually, and have achieved significant progress in increasing coverage through the UIP. However, there are still challenges that persist, and multiple determinants contribute to the existing challenges; parental migration is one of them. Migration has always been a key driver of socio-economic and demographic changes, particularly in low and middle-income countries (LMICs). Specifically, there is a need to better understand the vulnerabilities of immunization among recent migrants. To examine this, the study explores the association between a mother's recent migration and the full immunization coverage of children aged 12-23 months in India. Data & Methods-Our study utilized data from the National Family Health Survey-5 (2019-21). The outcome variable of interest in this study is the receipt of all basic vaccinations (full immunization) for children. The primary predictor variable in this study is the children's migration status. We used a series of multivariate logistic regression models to examine the relationship between full Immunization and recent migration of children, with some data restrictions in the models. Results - The results show a 17% difference in full immunization between migrant and non-migrant children. The odds ratios for children who had recently migrated were lower for full immunization (OR: 0.39, 95% CI: 0.35-0.43) compared to children who had not recently migrated. Even across the household wealth quintile and social groups, the recent migration of children was associated with being less likely to be fully immunized among children 12-23 months. Conclusion- The findings of this study provide significant quantitative evidence that recent migration (less than 3 years) of children is a key factor influencing Immunization coverage and is a predictor of full vaccination among children aged 12-23 months in India. The recent migration was consistently linked to a lower likelihood of full immunization coverage across different household wealth levels and social groups. This study suggests that recently migrated children are a vulnerable subgroup of the population at risk of not receiving all basic vaccinations by their first birthday.

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Development, Validation, and Implementation of a Stress Management Intervention for Rescue Workers in Rawalpindi: A protocol for a mixed-method study

Yasir, I.; Ahmad, I.; Bhatti, U. F.; Khan, S. A.; Malik, A.

2026-05-12 public and global health 10.64898/2026.05.09.26352786 medRxiv
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IntroductionOccupational stress among rescue workers is a major global public health concern. Rescue workers, including paramedics, firefighters, and disaster response teams, are consistently exposed to traumatic events, long working hours, physical hazards, and emotionally charged situations. These chronic stressors make them one of the most vulnerable groups to psychological distress, burnout, anxiety, depression, and post-traumatic stress disorders. In the local context of Pakistan, workplace mental health remains a neglected area. Despite stress and burnout being widely reported in these sectors, limited evidence-based interventions are available. Therefore, the study aims to develop and evaluate a locally tailored intervention to improve the mental health and psychosocial well-being of rescue workers. ObjectivesO_LITo develop a culturally appropriate stress management intervention to promote mental health for rescue workers in Rawalpindi. C_LIO_LITo validate the content and structure of stress management intervention for rescue workers C_LIO_LITo evaluate the effectiveness of stress management intervention for rescue workers in Rawalpindi C_LI MethodThe ethical approval of the study has already been obtained from the ethical review board of Health Services Academy (00013/HSA/PhD-2022) and Rescue 1122 District Headquarters, Rawalpindi. Data will be collected after obtaining informed written consent from relevant stakeholders. Data collection will start from April 2026 and will be completed in six months. Data compilation and results are expected by December 2026. Data collection will involve a scoping review to explore stress determinants and intervention components, and then a qualitative phase in which data will be collected through focus group discussions from potential Stakeholders (rescue workers, mental health experts, and program managers) to identify and validate stress determinants. Triangulation of data will be done to integrate qualitative findings with findings from the review. In the second phase, validation will be done by intervention development experts. The third phase aims to evaluate the effectiveness of the developed intervention using a quasi-experimental pre-post design. A total of 154 participants evaluated with the Perceived Stress Scale Score will be employed through a stratified sampling technique. The primary outcome is defined as remission from stress at 3 months, measured with the PSS. DiscussionIt is anticipated that the study will result in the development of a culturally appropriate and evidence-based stress management intervention for rescue workers, thus contributing to sustainable improvement in rescuers mental health and job performance.

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Engagement with communities at-risk of scrub typhus: lessons learned from Northen Thailand

Perrone, C.; Kanthawang, N.; Lee, S. J.; Horcharoen, W.; Phowkanta, T.; Cheah, P. Y.

2026-05-20 public and global health 10.64898/2026.05.16.26353374 medRxiv
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Background In northern Thailand, scrub typhus primarily affects rural and hill tribe communities, yet awareness is low. In 2020 we trained community health volunteers (CHVs) to raise awareness in their communities using a train-the-trainer approach. CHV knowledge rose dramatically. However, we did not assess the effectiveness in community members and our strategy relied heavily on CHVs, who have limited availability. Methods In a second phase, object of this manuscript and conducted in 2022-2023, after training CHVs we measured the effectiveness in community members and compared in-person sessions carried out by CHVs with sessions using video or audio recordings only. All materials included key information about scrub typhus transmission, symptomatology, prevention, and management and had been developed following feedback from participants from the first round of activities in 2020. Effectiveness was evaluated using a questionnaire assessing scrub typhus knowledge. CHVs were also asked to rate the feasibility of suggested preventative measures. Results A total of 74 community members participated in six sessions. Knowledge of scrub typhus significantly improved post-training (median score increased from 2 to 6 out of 9, p<0.001) and audio and video recordings were as effective as in-person trainings. CHVs noted that some of the preventative measures recommended are difficult to put in practice such as wearing gloves, washing daily after work, avoiding kneeling and resting on the ground, and washing clothes daily. Conclusions Our findings support the use of locally adapted multimedia training for scrub typhus prevention, showing that scalable formats can be as effective as in-person ones. Further collaborative work with people at risk should refine preventative messages to improve feasibility and acceptance.

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Predictors of Road Safety behaviors among Boda-Boda Operators and their passengers in Kampala: A Mixed-Methods Study

Ainembabazi, R.; Kimuli, D.; Murami, T.; Wafula, S. T.; mgeyi, E.; Kwesiga, J. B.; Kibingo, P.; Mugumya, I.; Atulomah, N. O.; Nsubuga, D.

2026-06-07 public and global health 10.64898/2026.05.29.26354085 medRxiv
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Background Despite existing road safety regulations, commercial motorcycle riders commonly referred to as "Boda Bodas" in Uganda continue to experience high rates of injuries due to road traffic accidents resulting from unsafe riding behaviours, contributing significantly to morbidity and mortality among both riders and passengers. Safe riding behaviours are less well documented, as well as factors associated with the observance of those behaviours. This study aimed to determine factors associated with safe riding behaviors for both boda-boda riders and their passengers in Kampala Central Division. Methods A cross-sectional survey study design was conducted using a convergent parallel mixed-methods design guided by the PRECEDE model. Quantitative data were collected from 424 riders through structured questionnaires administered by trained research assistants. Binary Logistic regression was used to determine the independent predictors of safe road riding behaviors, and Adjusted Odds ratios (AORs) have been reported. Data were analyzed using descriptive and inferential statistics, with a p-value <0.05 considered statistically significant. Qualitative data were collected simultaneously with quantitative data through in-depth semi-structured interviews with 10 passengers to capture perceptions of rider behaviors and safety practices. Thematic analysis was applied, and results were triangulated to highlight convergences and divergences between quantitative and qualitative findings, providing a comprehensive understanding of safety determinants for both riders and passengers. Results Of the 424 riders (mean rider age was 29.56 {+/-} 5.71), overall, 276 (65.1%) of riders exhibited unsafe riding behaviors. In the bivariate analysis with Logistic regression, predisposing factors (education, marital status, religion, and willingness to obey traffic regulations), and reinforcing factors (family encouragement) were significantly associated with safe riding behaviors. However, in the adjusted model, secondary (AOR=0.50; 95% CI:0.30-0.85) and post-secondary education (AOR=0.57; 95% CI:0.33-0.98), being married (AOR=0.56; 95% CI:0.34-0.91), Christian religion (AOR=2.98; 95% CI:1.63-5.47), willingness to obey traffic regulations (AOR=0.41; 95% CI:0.24-0.70), union advocacy (AOR=1.76; 95% CI:1.03-3.01), and well-maintained roads (AOR=1.65; 95% CI:1.07-2.55) were significant predictors of safe riding behaviors. Qualitative interviews further highlighted barriers to safety, including a lack of helmets, over-speeding, disregard for traffic regulations, and poor road infrastructure. Conclusions Rider and passenger safety is still low, interdependent, and influenced by multiple factors. Integrated interventions focusing on education, stronger families, religious affiliations, union safety advocacy, and stricter enforcement of traffic regulations are vital for enhancing safety for both riders and passengers.

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Individual and system causes of moral distress experienced by public health practitioners in Canada

Bennett, J.; Pakhale, S.; Desmond, N.

2026-06-03 public and global health 10.64898/2026.06.02.26354688 medRxiv
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Aims Moral distress has been studied across many health arenas; however, public health has often been overlooked. Canada is facing a healthcare crisis with a significant number of staff leaving the healthcare field. This study explores the experiences of moral distress in public healthcare practitioners across Canada. Better understanding these experiences can provide insights into how to support staff and prevent attrition in public health. Methods This was a cross-sectional qualitative study. Fifteen in-depth interviews were conducted between May and July 2023, through remote and in person methods. Participants were from nursing, social work, medicine, and dietetics, all working in public health across Canada. Iterative thematic analysis was used. Emergent themes were compared within and across data sets and by participant age and years of experience. Results/Findings Experiences that contributed to moral distress included systemic powerlessness, political and ideological overreach, unethical work environments and undervalued expertise. Years of experience and diversity in gender and ethnicity impacted how practitioners navigated moral distress. Experiences where practitioners felt actions went against their values increased during the pandemic, contributing to moral injury. Conclusions This study situates the unique position of public health within the health system and explores experiences of moral distress both during and outside the COVID-19 pandemic. While the pandemic brought the concept of moral distress to the forefront of many peoples minds, these experiences existed prior. Addressing the underlying causes will contribute to establishing approaches to support public health practitioners suffering from moral distress and injury.

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Predictors of poor glycemic control among adults attending a peri-urban diabetic clinic in Wakiso district, Uganda: A cross-sectional study using modified Poisson regression analysis.

Larissa, K. N. Y.; KOOKO, R.; Musoke, D.; Rutebemberwa, E.; Nakisita, O.; Dandy, M. W. W.; Somse, P.

2026-06-03 public and global health 10.64898/2026.06.02.26354687 medRxiv
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Background: Poor glycemic control, a contributor to the development of diabetes related complications among patients with diabetes mellitus, remains a public health challenge in low- and middle-income countries. In Uganda, limited evidence exists on predictors of poor glycemic control among diabetic patients attending peri-urban primary healthcare facilities. The study assessed predictors of poor glycemic control among adults attending the diabetic clinic at Kasangati Health Centre IV in Wakiso district. Methods: We conducted cross-sectional study among 283 diabetic patients attending Kasangati Health Centre IV between March and April 2025. Data were collected using interviewer-administered structured questionnaires and data abstraction tools. Poor glycemic control was defined as glycated hemoglobin (HbA1c) levels [&ge;]7%. Modified Poisson regression with robust standard errors was used to determine factors associated with poor glycemic control. Adjusted prevalence ratios (aPRs) with 95% confidence intervals (CIs) were reported. Results: Overall, 67.8% of the participants had poor glycemic control. Poor glycemic control was significantly associated with older age, low income status (aPR: 1.4, 95%CI: 1.24-1.58), use of multiple anti-diabetic medications, non-adherence to regular follow-up (aPR: 1.5, 95%CI: 1.33-1.65), medication side effects (aPR: 1.2, 95%CI: 1.01-1.32), physical inactivity (aPR: 1.1, 95%CI: 1.05-1.21), non-adherence to recommended dietary plans (aPR: 1.1, 95%CI: 1.02-1.22), perceived treatment regimen complexity (aPR: 1.2, 95%CI: 1.12-1.34), stress (aPR: 1.1, 95%CI: 1.08-1.20), lack of peer support groups (aPR: 1.2, 95%CI: 1.08-1.23), and high costs of accessing care (aPR: 1.2, 95%CI: 1.17-1.33). Conclusion: Almost two-thirds of the diabetic patients suffered from poor glycemic control which was determined by various socio-economic, behavioral, clinical and health system factors. Enhancing adherence counseling, encouraging healthy lifestyles, adopting age-based supportive healthcare approaches, better psychosocial support and reduction of cost barriers in accessing diabetic healthcare could improve the glycemic status of diabetic patients in peri-urban primary healthcare settings.

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A Study To Analyse The Demographics And Injury Pattern Of Dog Bite Cases In Emergency Department Of A Tertiary Care Hospital In Chennai

Vinoth, D.; kumar, A.; jenifer, E.

2026-05-22 public and global health 10.64898/2026.05.20.26353645 medRxiv
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ABSTRACT Background Dog bite injuries are a major yet largely preventable public health concern worldwide. They contribute significantly to morbidity, healthcare burden, and economic costs, particularly in emergency department .The present study aims to analyse the demographics and injury pattern of dog bite cases presenting to the emergency department of a tertiary care hospital in Chennai. Methods We conducted a cross-sectional study with dog bite injured participants attending the Causality from November 2025 to April 2026 data was collected using a structured tool including details on demographics (Age, Gender, Education) injury related characteristics , history of pure bite site of dog bite injury type, WHO bitten criteria and information to management etc. We used here non probability statistical analysis and age specific dog bite cases and independent variables were analysed using SPSS (2.0 version). Result A total of Two hundred sixteen dog bite cases were analysed in the study by period of 6 months The majority of participants were 172 (79.6%) were above 18 years and 44 (20.4) were below 18 year, 130 (60%) from rural areas and 86 (39.8%) from urban areas, 136 (63.0%) of Victims presented within a day of the bite, 61( 28.2) next day and 19 (8.8%) in after one week 66 (30.6) were bitten by own dog and 150(69.4%)were bitten by neighbour / friended dog. 124(57.4) were bitten by stray dog 92(42.6) bitten by pet dog. 117(54.2) were vaccinated dog and 99(45.8%) were not vaccinated .110(50.9) victims were injured by laceration. 26(12.0%) were injured by puncture wound.46(21.3) were injured by abrasion 10(4.6) were injured by avulsion 15(6.9%) were injured by crush injury. 156(72.2%) were had minor wound.45(20.8%) victims had moderate wound and 15(6.9%) victims had severe wound. 112(51.9%) victims were taken antibiotics.104(48%) were not taken antibiotics. 185(85.6%) victims received tetanus toxoid, 31(14.4%) were not received tetanus toxoid. CONCLUSION There is a high burden of dog bite injuries from stray dogs in India. Despite early hospital presentation in many cases gaps in first aid practices and rabies post exposure prophylaxis were evident and highlighting inadequate awareness. Key words Rabies immunoglobulin, Dog bite, WHO criteria, Anti rabies vaccine, stray Dog, wound

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Diverging Pre-Pandemic Mortality Trends: Age-Specific and Cause-Specific Patterns Across High-Income Countries

Perez-Reche, F.; Summers, J.; Jones, G. T.; Macfarlane, G. J.

2026-06-03 public and global health 10.64898/2026.06.01.26354619 medRxiv
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Background: Mortality rates have declined across most high-income countries for decades, but recent evidence suggests a slowdown in improvements or a shift to increasing mortality, particularly among working-age populations. The international distribution and drivers of these trends remain incompletely understood. Methods: Mortality trends during 2012-2019 were analysed using all-cause and cause-specific data from 30 countries. Trends were estimated via linear regression. K-means clustering with Dynamic Time Warping identified countries and ICD-10 chapters with similar temporal trajectories. Results: Trends varied substantially by nation. While Japan, Switzerland, and the Republic of Korea maintained consistent declines in all-cause mortality rates, increases were concentrated in the United States, Canada, and the United Kingdom, most prominently in persons aged 30-59 years. However, cause-specific analysis showed that rising mortality was not confined to these countries: most countries exhibited increases in at least one ICD-10 chapter, with several European countries showing increases across multiple chapters. Across countries, a small set of causes recurred among increasing trends, including external causes (self-harm, drug poisoning) at younger ages and chronic conditions (cardiovascular and liver diseases, specific cancers) in mid-life. Notably, ill-defined causes of death consistently appeared among the increasing causes across countries and age groups. Conclusions: Mortality increases in the 2010s were geographically more widespread than previously recognized. The recurrent rise in mortality from ill-defined causes suggests that an important component of mortality change remains poorly characterized. These findings indicate that stalled health progress is a systemic challenge across many high-income societies.

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Linking School Stress and Psychosomatic Complaints in South Tyrol, Northern Italy: Parental and adolescents perspectives in a cross-sectional design

Barbieri, V.; Piccoliori, G.; Engl, A.; von Strobele Prainsack, D. H.; Wiedermann, C. J.

2026-05-30 public and global health 10.64898/2026.05.26.26354140 medRxiv
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Background School stress and psychosomatic complaints are linked and increase in high-income countries, with differences between countries. Evidence of how these parameters develop in Italy, particularly through combined parental and self-reported perspectives across age and gender, is limited. Methods A population-based online survey investigated school stress and psychosomatic complaints in children and adolescents aged 6-19 years, analyzing proxy- and self-reported data based on standardized validated instruments. Data was stratified by gender and age for children (6-10), early adolescents (11-14), and late adolescents (15-19). Results For early and late adolescents, the gender gap was evident, with higher levels of stress and health complaints in late adolescent girls. In this group, 56% of the girls self-reported rather/high school stress, and 43% of the boys. Parents perceived school stress and psychosomatic problems of their children as less severe than adolescents themselves. Parents stated a higher effect of parental help with school problems, and a lower effect of physical activity and digital media use on their childrens psychosomatic problems. Physical activity was related to fewer psychosomatic complaints, especially in girls. Conclusions This study identified late adolescent girls as vulnerable group, underscoring the critical need for gender-specific early prevention strategies starting in childhood, particularly for families with lower socioeconomic status. Parental perspectives may underestimate adolescents stress levels and psychosomatic well-being. In early adolescence, less digital media use may prevent psychosomatic problems, in late adolescence, physical activity may be a preventive method. Further longitudinal investigations should put a special focus on self- and proxy-reported perspectives.